There is a quite strong evidence for a positive association between Helicobacter pylori infection and gastric cancer risk [6]. Only a small proportion of all infected individuals develop gastric cancer. Those with duodenal ulcer seem to be protected and so it has been postulated that certain circumstances might modify the relationship between H. pylori infection and gastric cancer [7]. Factors of importance include age at infection, characteristics of the host such as gastric acid secretory...
Parkinson is a neurodegenerative, slowly progressive neurological disease which develops when certain nerve cells of the brain, in a region called the substantia nigra, die or become impaired. It affects muscle control, and balance, associated with the loss of dopamine-producing brain cells which are referred to as parkinsonisms. To date there has been little agreement on what is the best treatment for Parkinson disease. Levodopa (L-DOPA) has been widely used as the main drug to treat...
Referring to the chemical structure it can be seen that bupropion has a fairly hydrophilic core benzene ring and polar groups such as the chloro-group, amine and ketone. The amine group does increase water solubility because it is polar but more importantly it is ionisable which significantly increases the water solubility (Jamie, 2011): Bupropion has a pKa of 7.9 (O'Byrne et al., 2010). The amine on the carbon chain can act as a weak base: The partition coefficient (logP) equalled 3.21: drugs...
The aims of the investigation is to measure the pressure distribution on the surface of a smooth cylinder placed with its axis perpendicular to the flow and to compare it with the distribution predicted for frictionless flow, and to calculate the drag coefficient of the cylinder. In the investigation being carried out, a cylinder in a closed circuit wind tunnel will be experimented upon to gather the pressure distribution acting on it at different speeds. When the cylinder is standing...
The present contribution deals with size controlled synthesis of silver nanoparticles through green route by using sulfated polysaccharide isolated from marine red algae by controlling the pH. These nanoparticles were well characterized by UV/Visible spectroscopy, HRTEM, X-ray diffraction and zeta potential measurement. The obtained silver nanoparticles showed surface plasmon resonance (SPR) centered at 404 nm with average particle size measured to be 15±3 nm. The dose dependent effect...
Abstract: Darwin's theory of descent with modification through natural selection is an essential theme that can be observed in almost every aspect of biology. Competition between species is one of the most significant forces in determining which species flourish and which species go extinct. The species that is able to outcompete its challengers in order to attain or maintain its ecological niche has a better chance of survival and reproduction. Specifically, within the genus Geospiza,...
Power supplies are used for making computer system weather it is desktop or tower to it is laptop it is must used. Here only desktop based computer's power supplies are mentioned. A poor power supply can reduce the life time of a computer system. On the other hand a high quality Power supply can help to reduce the noise or heat generated within a computer system. So we should use good quality power supply but how we can come to know that this is good and this is bad power supply here are some...
Carcinoid syndrome is a collection of symptoms that is associated with carcinoid tumours. Carcinoid is a cancer of the neuroendocrine system; neuroendocrine cells are spread throughout the body in organs such as the small intestine, appendix, colon, rectum, bronchi, pancreas, ovaries, testes, bile ducts, liver, as well as other organs. 1, 2, 9 Neuroendocrine cells are known to be able to produce many types of hormones, for instance, histamine, serotonin, dopamine and tachykinins. Carcinoid...
Osteoarthritis is a chronic musculoskeletal disorder characterized mainly by the progressive degradation of the articular cartilage and aging. Diagnosis of osteoarthritis is usually made at an advanced stage of cartilage destruction. Efforts are on-going to identify specific markers that might help in early diagnosis, monitoring disease progression and therapeutic intervention. To facilitate the identification of such markers, an in-depth proteomic analysis of osteoarthritis synovial fluid, the...
Identify which mediators, along with histamine, are involved in anaphylaxis including: The effects the release of these substances has on the vascular and respiratory systems; Anaphylaxis happens when the body makes the wrong kinds of antibody, a kind called immunoglobulin E (IgE for short) to protein in our food or to something like a drug. IgE sticks to cells in our bodies (mast cells and basophils) which can release substances which have powerful effects on our blood vessels and air...