Atherosclerosis, an inflammatory disease of the blood vessels, is the leading cause of death in the Western world. Omega-3 fatty acids have been shown to promote good cardiovascular health and prevent atherosclerosis. They have also been shown to prevent obesity, a risk factor for cardiovascular disease. The typical American diet, though, is not sufficient in omega-3 fatty acids and is high in omega-6 fatty acids, which are pro-inflammatory. Mammals lack the ability to synthesize omega-3...
Introduction DNA typing was first used in Great Britain for law enforcement purposes in the mid- 1980s and has revolutionized forensic science and the ability of law enforcement to match perpetrators with crime scenes. It wasn't employed in the United States until 1987. DNA profiling has changed forensic science. DNA technology has given police and the courts a means of identifying the suspects of rapes and murders. Thousands of cases have been closed and innocent suspects freed with...
Embryonic heart morphogenesis is a complex and dynamic process that is incompletely understood, but critically important for long-term survival.The heart begins as a linear tube of myocardium lined with endocardial cells that functions like a suction pump (Forouhar et al., 2006), but quickly loops and grows into a four chambered heart complete with valves and septa that pumps in a piston manner. This process involves several key events that happen in three dimensions, including linear heart...
In conventional agricultural system, one of the major concerns is to reduce the abundance of unwanted pests known as weeds. In most of the cases, removal of the weed population in agricultural fields involves the application of chemical herbicides, which has been successful in increasing crop productivity and quality. However, concerns regarding the environmental and economic impacts of herbicide applications have promoted interests in seeking alternative weed control approaches. An automated...
Mammalian target of rapamycin is a serine/threonine kinase that directly regulates protein synthesis upon activation through an extensive network of upstream signalling. mTOR is involved in a vast array of cellular activities including transcription, translation, cell size, mRNA turnover, protein stability, cytoskeletal organization and autophagy. Activity of this mTOR signalling network is regulated largely by metabolic stimulants comprised of growth factors, nutrient availability such as...
To investigate the involvement of apoptosis in the pathogenesis of hyperthyroidism and T3-induced pulmonary hypertension in the broiler chickens, expression of caspases (1, 2 and 3) genes were evaluated by semiquantitative RT-PCR in the lung and left/right heart ventricles. One-day-old fast-growing chickens were randomly divided into two equal groups with three replicates per group. Chicks were reared for 7 weeks under standard conditions. Thyroid hormone (T3) was added to the ration (1.5 mg...
Chromatography - International Union of Pure and Applied Chemistry has defined the chromatography as 'it is a technique which is primarily used for the separation of the components in the sample, where the components of the sample are distributed between two phases, which are the stationary and mobile phases. Solid, gel and liquid supported on a solid material can be used as a stationary phase, which may be distributed as a film, spread as a layer or packed in specific columns. Liquid or gas...
Enzymes are very efficient natural biological catalysts; they speed up chemical reactions in living organisms. They are large protein molecules which are made up of long chains of amino acids. The shape of the enzyme is determined by the shape of the amino acid chain - the number of amino acids. The shape of an enzyme is the key feature to how it works. Depending on the enzyme, some may break down large molecules to smaller ones and some enzymes join two molecules together. How enzymes work can...
Stem cell research and its use as a treatment has been the hottest topic for debates from the last few years. Stem cells are a special kind of cells in the body which have the potential to regenerate damaged tissue in the body by developing into other types of cells like liver cells, heart cells, etc. Stem cells normally function in the body to maintain optimal health by replacing dysfunctional cells. There are three different types of stem cells depending on their source which are embryonic,...
The present research work was aimed to develop matrix tablets of Aceclofenac with Aloe barbadensis miller leaves mucilage and Poly Vinyl Pyrrolidone and to study its functionality as a better matrix forming combination for sustained release tablet formulations. Mucilage from Aloe barbadensis miller leaves was extracted, purified and characterized for its physicochemical characteristics. The powdered blend was evaluated for flow properties. Various formulations of Aceclofenac with Aloe...