The pathogenesis of pulmonary hypertension is a complicated, multifactorial process in which the combined effects of pulmonary artery vasoconstriction, vascular remodeling and thrombosis involve to a continuous high pulmonary vascular resistance. Vascular remodeling is associated with the low-grade inflammation, vascular fibrosis and apoptosis. Apoptosis, or programmed cell death, is a multi-pathway biological process, which contributes in many physiological and pathological phenomena....
The term bioinformatics was coined by Paulien Hogeweg, in 1978. He said that the term Bioinformatics referred to the study of information processes in biotic systems. Bioinformatics, the application of computational techniques to analyze the information associated with biomolecules on a large-scale, has now firmly established itself as a discipline in molecular biology, and encompasses a wide range of subject areas from structural biology, genomics to gene expression studies [2]. Bioinformatics...
Introduction The purpose of this literature review is to analyze relevant literature and research done on the topic of genetic therapy treatment for rheumatoid arthritis (RA). There exists a large body of literature that supports the feasibility and prospect of creating a new standard of care for RA patients. Several key original studies are examined here, as well as significant reports on current and promising treatments for RA. This review is divided into four sections as follows:...
Shiga toxin-producing Escherichia coli organisms (STEC) are pathogens that have ability of producing sporadic and epidemic diarrhea, hemorrhagic colitis, bloody diarrhea (BD), non-bloody diarrhea (NBD), and potentially life threatening hemolytic-uremic syndrome (HUS). Non-O157 STEC serotypes can also cause serious illness, but their impact as pathogens remains unknown (Leotta et al., 2008; Nagy et al., 2008; Hedican et al., 2009). Shiga-like toxin (SLT)-producing E. coli has been associated...
Diet has for years been known to play a decisive role in the development ofchronic diseases. At the end of the 20th century there has been a prominent change in food habits almost all around the world. Food consumption has changed from a traditionally plant based diet containing complex carbohydrates and dietary fibers present in vegetables, fruits and berries to a diet rich in saturated fats and simple carbohydrates i.e. a diet consisting mainly of meat and products with high energy content....
The major goal of today's wireless communication system is to develop a reliable, bandwidth efficient, Intersymbol Interference (ISI) free and high data rate communication system. OFDM (Orthogonal Frequency Division Multiplexing) is the key digital communication technology of the current decade. In this paper Wavelet based OFDM scheme is used instead of  OFDM scheme,  the conventional Fourier based exponential carriers of multicarrier system is replaced with orthonormal  wavelets and the...
The aim of this essay below is to explain homeostasis, the principles involves, the negative feedback, the control of the blood glucose level, the mechanism of temperature regulation and the structure of the kidney and the function and the hormonal control of osmoregulation. Homeostasis is the process of keeping the body environment in a steady state. The importance of this is that a great deal of the hormone system and autonomic nervous system is dedicated to homeostasis. The factors that need...
A polymer is a large material which consists of many small units, called monomers, chemically bonded with each other William, Hashemi Prakash, 2008. Polymers form an integral parts of our daily life, some examples are: nylon, rubber and plastics. It is by the grace and work of Dr Hermann Staudinger that today we are able to manufacture synthetic polymers (Nobleprize.org, 2009). The average world consumption of plastics is 26 Kg (plastics industry-statistics, 2008). Polymer can be classified...
One of the advantages of conducting laboratory studies is that they allow researchers to control a range of conditions that could potentially impact the outcome of a study. Environmental factors, water quality, loading rate, chemical exposure, study animals, animal husbandry and health can all be manipulated more easily to identify actual treatment effects in laboratory studies. 3.1.1 The objective of (Hayes et al. 2002a) study was to find whether atrazine interfere with metamorphosis and sex...
As the famous aphorism by Francis Bacon states, "knowledge is power." This sentiment seems particularly applicable to the field of human genetics, which has relatively recently been significantly augmented by the completion of the Human Genome Project. The project, which successfully identified the genes in human DNA and determined the sequence of billions of base pairs, opened up a wealth of revolutionary information that has led to a new understanding of human biology and ways to...