Simvastatin is a hypolipidemic drug used to control hypercholesterolaemia. It is a semi-synthetic statin based on lovastatin (NICE 2008). It is licensed to be used for the treatment of Primary hypercholesterolaemia, mixed dyslipidaemia, homozygous familial hypercholesterolaemia as an adjunct to diet and other lipid-lowering treatments and the reduction of cardiovascular mortality and morbidity (NICE 2008). Pharmacological Properties: Pharmacodynamics: Simvastatin is given orally in a usual...

INTRODUCTION: Tea is one of the best refreshing drinks which have been using Worldwide since from hundreds of years. First discovered in China several years ago and later on it became popular in Japan, India and almost in all the parts of world. Different varieties of tea are available like green tea, black tea, oolong tea, white tea etc depending on the type of fermentation process. Tea is obtained from leaves, twigs, and leaf buds of Camellia sinensis species belonging to the family Theaceae....

The blockers are drugs which act by blocking the effect of mediators and agonists on the relevant receptors. The -blockers show an antihypertensive effect, which is caused by reduced cardiac output, decreased release of renin, central decrease of sympathetic action. Also, they exhibit an antianginal effect, which is caused by slowing of the heart rate and thus decreased metabolic demand. The main side effects of general -blockers are cardiac failure, such as cardiac depression, hypotension,...

Objective; To carry out an overview of the medical treatment of the benign prostatic hyperplasia using the combination drugs of alpha adrenagic uro selective blockers( Tamsulocin, Alfuzocin) and 5 Alpha reductase iso enzyme 1&2 inhibitor - dutasteride. Data Source; Review of literature of multicenter international control trials, plus those in the local scene. Data Selection; Selected articles from international papers on BPH from international research groups (See Appendix) and the...

This presentation will present information on current long-term mechanical support applications and future trial designs for investigation affecting this public health issue. At the conclusion of this lecture, the participant will be able to: 1. Identify the different mechanical support devices available and give an overview. 2. Compare and contrast optimal medical therapy and destination VAD therapy including looking at REMATCH trials and any other pertinent trials. 3. Understand the...

A great number of industries such as textile, printing, paper and pulp, petroleum, iron-steel, pesticide, paint, solvent, pharmaceutics, consume large volumes of water, and organic based chemicals. These chemicals show a large difference in chemical composition, molecular weight, toxicity, etc. In addition effluents of these industries contain undesired quantities of these pollutants and need to be treated [Aksu 2005]. This highly colored industrial effluents substantially affect...

There are three strata or layers that may be found in plant cell walls. The outmost layer or middle lamella forms the crossing point linking neighboring plant cells and bonds them as one. This is a layer rich in pectin. The primary cell wall is commonly a slender, stretchy and expandable layer that forms while the cell is maturing. The secondary cell wall forms within the primary cell wall once the cell is done maturing. It isn't common in all cell types. In some cells the secondary...

Infrared spectroscopy is the most powerful technique use in the analytical laboratory. Infrared spectroscopy is associated with the infrared region. There are number of compounds (organic and inorganic), which absorbed various frequency of electromagnetic radiation. Infrared region divided into three types; near- IR, mid- IR, far- IR. In terms of the wave length near-IR region extends from 1400cm-1-4000cm-1, mid-IR from 4000cm-1-400cm-1 and far -IR from 400-10cm-1 . Main function of the...

The genetics of ageing in worms and humans. It was once said that age is a prison from which no man can escape. Nevertheless scientists are trying their best to understand this feared process that haunts so many. People are familiar with what it is like to grow old, but when it comes to comprehending the intricate causes of ageing, the scientific community is still unable to reach a conclusion. Amongst the wide range of model organisms being used to study gerontology, the free...

A 35 year old female patient has been diagnosed with an acute exacerbation of multiple sclerosis (MS). Women make up 70% of the MS population but this gender preference remains unexplained. Thus, this patient is naturally more susceptible to getting MS as the patient is a female and falls into the 20-40 year old age bracket. In Scotland, 1 in 500 people have MS with women almost twice more likely than men to get the disease in general1,2. Also, about 1800 to 3400 people are newly diagnosed...