Detection Of Diabetic Retinopathy
Automated detection of lesions in retinal images can assist in early diagnosis and screening of a common disease: Diabetic Retinopathy. A robust and computationally efficient approach for the localization of the different features and lesions in a fundus retinal image is presented in this paper. Since many features have common intensity properties, geometric features and correlations are used to distinguish between them.India ranks second in diabetes in the world. We show how to prevent the...
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Up Regulation Of High Mobility Group
Peripheral nerve injury induces neuropathic pain through the up-regulation of inflammatory mediators in the spinal cord. The high mobility group box 1 (HMGB1) is recognized as a cytokine-like mediator of delayed endotoxin lethality and acute lung injury, and is associated with the pathogenesis of many CNS diseases. In this study, we examined the change of HMGB1 expression as well as glia activation in the spinal cord and pain behaviour after spared nerve injury (SNI).Methods. After rats...
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Beta-cell functionality
CHAPTER 6 In physiological situations such as pregnancy, beta-cell mass expansion is generally associated with beta-cell function enhancement to accommodate the new insulin requirement particular to the pregnant state (Sorenson and brelje 1997, horm metab res). Similarly during obesity, an augmentation of both beta-cell number and beta-cell responsiveness is also observed to compensate for the insulin resistance induced by this state, a key trait of this condition (Kargar and Ktorza, Diabetes,...
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The Cause And Cellular Mechanisms Of Cancers
Cancer malignant tumour begins with the genetic alteration of a single cell, leading to continuous proliferation and resulting in an invasive mass that ultimately can kill the organism. Cancer consists of more than 100 types, depends on the location of cell and the genetic aberration in the body. Cancer has such features as uncontrolled cellular proliferation, growth without appropriate signals, ability to escape from apoptosis, intrusion and destruction of adjacent tissues and ability to...
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Progression From A Single Cell
Cancer is defined as any malignant tumor that arises from uncontrolled normal cell aggregation therefore leading to dedifferentiation, invasion and local destruction of surrounding tissues. Cells are the building blocks that make up the human body. Progression from a single cell, aggregates of which forms a tissue, then an organ and finally the system highlights the importance of governing the function of this unit. Cancer Research UK's Cancerstats revealed that the incidence of new cancer...
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Kinematic Differences In Horses Bare Legged Or Bandaged
The purpose of this study was to assess if there was any kinematic differences in the flexion angle of the carpus between horses wearing sports boots and exercise bandages and horses with bare forelimbs while trotting. The hypothesis of the study was that there would be a significant difference in peak flexion angle of the knee between horses with boots, bandages and untreated limbs. Kinematic data was collected from six adult Warmblood horses in this study. The horses had a...
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the cleveland bay horse breed
Chapter 7 - Discussion The Cleveland Bay - A Breed with a History and a Future Introduction The project reported in this thesis set out to examine the genetic status of the Cleveland Bay Horse through pedigree and molecular methods as well as to evaluate the effectiveness of a breed management scheme. Each of the previous four chapters has examined one aspect of this analysis. This chapter presents a summary, appraisal and evaluation of the various findings of this study and examines the...
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Human Body Organisation And Structure
In this essay I will be looking at the human body and how it is organised, from the simple cell to how the body systems co-operate with each other and that everything functions properly. Firstly I will be looking at some simple cells that will group together to make up a tissue. The first cells I will be looking at will be the erythrocytes, the ova cells in women, the spermatozoon cell in men and the epithelial ciliated cells in the throat.The erythrocytes are made in the red bone marrow of ...
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The Radioactivity Decay And Radiation
The alpha particle was discovered and named in 1899 by an English scientist, Ernest Rutherford while working with uranium (1). Rutherford and his co-workers used alpha particles in experiments to probe the structure of atoms in thin metallic foil. From 1909 to 1911 this work achieved the first concept of the atom: a tiny �planetary system� with negative charged particles, electron, orbiting around a positively charged nucleus, through the Rutherford-Bohr planetary model of the atom...
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Nitric Oxide After Bacillus Calmette Guerin Treatment
The majority of Bladder Cancer cases are Transitional Cell Carcinomas (TCC). Treatment with Bacillus Calmette-Guérin (BCG) bladder instillations is an established treatment modality for superficial urinary bladder cancer and carcinoma in situ (CIS) but only 70% of patients respond to treatment. The exact mechanism of how BCG induce tumour remission is still unknown. Earlier reports put forward the idea that BCG induces an inflammatory response which activates macrophages resulting in...
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